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Puriflash: The Pursuit of Purity

Click the links below to learn more about PuriFlash
           NEW! Dry Load Columns
           NEW! Decolorization
           Instruments
           Columns
           High Speed
           High Throughput
           High Capacity
           Guaifenesin Enantiomers
           High Throughput Chiral
           Reverse Phase
           High Sensitivity
           Diastereomers
           Crude Reaction Mixtures
           ELSD
           Flash Phases
           UPFP (Ultra-Performance
           Flash Purification)

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Ultra Performance Flash Purification

Ultra Performance Flash Purification (UPFP)

UPFP = High Efficiency Columns + High Flow Rates

Interchim has greatly improved the throughput in flash purification with the introduction of UPFP. By reducing the particle size in the columns and increasing the flow rate, purification can now be done three times faster, drastically reducing run times. Click to view Test Conditions


The seven minute run in the graph to the right uses a 15µ, 25g column at 40 ml/min. The resulting flow is double the rate which is typically considered for a 25g column. Despite the increased flow rate, resolution is superior to a standard 40-60µ column and completed in a fraction of the time.

Increased pressure is a factor in UPFP, but it is easily managed with columns that are stable to 320 PSI / 22 bar. The puriFlash puriFlash evo system is rated to 425 PSI / 30 bar.

The puriFlash HP 30µ columns operate at the same pressure when compared to conventional 40-60µ flash columns. This is a result of the highly efficient spherical silica improving flow mechanics and permeability.

Interchim provides the systems and columns to make the most of Ultra Performance Flash Purification.UPFP Column

 

 

Interchim  |  1536 West 25th Street, Suite 452, San Pedro CA 90732 - USA |  Tel 800.560.8262 |  Fax 310.802.3877