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Applications | Chiral Purification
Affordable chiral purification is now a reality. SureFlash columns are packed with a variety of chiral stationary phases which match those used in analytical development.
SureFlash columns are stable up to 80 bar/1160 PSI and use axial compression to compensate for voids at the inlet which may develop over time.
| Phase | 250 x 10 mm 80 bar/1160 PSI |
Price $ | 250 x 15 mm 70 bar/1015 PSI |
Price $ |
|---|---|---|---|---|
| Chiralpak AD 20 μm | SF10101 | 2900 | SF20101 | 3600 |
| Chiralpak OD 20 μm | SF10102 | 2900 | SF20102 | 3600 |
| Chiralpak IA 20 μm | SF10103 | 3200 | SF20103 | 3600 |
| Chiralpak IC 20 μm | SF10104 | 3200 | SF20104 | 3600 |
| Phase | 250 x 25 mm 50 bar/715 PSI |
Price $ | 250 x 50 mm 30 bar/435 PSI |
Price $ |
|---|---|---|---|---|
| Chiralpak AD 20 μm | SF30101 | 5900 | SF40101 | Quote |
| Chiralpak OD 20 μm | SF30102 | 5900 | SF40102 | Quote |
| Chiralpak IA 20 μm | SF30103 | 6200 | SF40103 | Quote |
| Chiralpak IC 20 μm | SF30104 | 6200 | SF40104 | Quote |
The analytical method was scaled up from a 250 x 4.6 mm to a 250 x 15 mm column. 100% purity was achieved on sample loads of 40 mg and 120 mg. The column was run on the puriFlash 430 at an average pressure of 7 bar. Based on the scaling factors a 250 x 50 mm column would be suitable for sample loads in excess of 1 gram. |
Test Conditions:
|
Test Conditions:
| Mobile Phase: | 90:10 Heptane:Ethanol + 0.2% DEA |
| Analytical: | 250 x 4.6 mm, 10 μm particle size 1.0 ml/min, 450 PSI |
| Preparative: | 250 x 15 mm, 20 μm particle size 11.0 ml/min 7 Bar / 100 PSI |
| UV: | 280nm |
Test Conditions:
| Gradient: | 5—7% B over 10 minutes A: Heptane + 0.2% DEA B: Ethanol + 0.2% DEA |
| Analytical: | 250 x 4.6 mm, Chiralpak AD 10 μ particle size 1.0 ml/min, 450 PSI |
| Preparative: | 250 x 15 mm, Chiralpak AD 200 μ particle size 11.0 ml/min 7 Bar / 100 PSI |
| UV: | 280nm |